Enhanced Health & Immunity

By Dr. Nick Zyrowski

An estimated 42 percent of Americans have a vitamin D deficiency, which is linked to cardiovascular issues, cancer, decreased immune function, autoimmune diseases, and cognitive decline. With these staggering statistics, one may ask why more people aren’t boosting their intake of vitamin D? The truth is – many are afraid of taking “too much” because it could cause a vitamin D toxicity.

Current Recommendations

The National Institute of Health (NIH) suggests a daily vitamin D dose of 600 international units (IU) per day, along with a warning about the risks of exceeding safe limits due to potential toxicity. However, some research shows that higher doses could offer benefits beyond bone health, and that our fear of vitamin D toxicity may be causing us to not get nearly enough for optimal health.

Dr. Patrick McCullough, a board-certified internist, documented three cases in 2019 where patients taking high doses of vitamin D (20,000–60,000  IU  daily)  for  years  experienced  health improvements. One asthma patient, who started at 10,000 IU daily, lowered his asthma exacerbations significantly and eventually increased to 30,000 IU. Another patient saw improvements in a hand lesion thought to be cancerous, and a third with extensive psoriasis saw his skin condition clear up.

Current NIH guidelines are based on recommendations from the 2010 Institute of Medicine (IOM), which set a daily intake of 600 IU to achieve serum levels of 20 ng/ml, with a 4,000 IU upper limit. However, some experts, including Dr. McCullough, believe this is below the body’s physiological needs, suggesting that up to 10,000 IU daily is safe. Both the Council for Responsible Nutrition and the Endocrine Society support this, acknowledging that vitamin D plays a role beyond just bone health.

The Vital Role of Vitamin D

Vitamin D is needed by every cell in the body. All cells have a receptor for vitamin D and it is the only vitamin that our body can produce on its own. This highlights how important vitamin D is for your body to carry out important daily functions.

Vitamin D affects over 2,000 genes, regulating immune function, neural activity and metabolic pathways, suggesting it functions more like a hormone than a traditional vitamin. Though it can be synthesized through sunlight exposure, it is difficult to achieve 30 minutes a day from sunlight alone especially while living in the cloud-covered winters of Michigan.

Dr. Ana Mihalcea, a board-certified internist, found that most of her patients benefit from 10,000 IU daily, achieving improved cognitive and energy levels. Dr. Joseph Bosiljevac observed variability in optimal levels among patients as well.

In autoimmune conditions, high doses of vitamin D have been used with therapeutic success. And patients with multiple sclerosis have reported significant improvements with this regimen, as have those with rheumatoid arthritis, lupus and Crohn’s disease. Vitamin D also supports cancer prevention and mental health. Studies link higher levels to a reduced risk of cancer, anxiety, depression and Alzheimer’s disease.

How Much Vitamin D Do You Need?

Given these broader health implications, many experts, including myself, advocate for re-evaluating current vitamin D guidelines to better support individualized health needs.

I recommend taking vitamin D with K2 and magnesium to mitigate toxicity risks, as these nutrients help deposit calcium in bones instead of arteries. Most of my patients are taking between 5,000 – 10,000 IUs of vitamin D daily to achieve adequate vitamin D levels. Conditions like obesity and inflammation can affect vitamin D absorption, so testing serum levels is advisable. If you have not been tested for Vitamin D recently, it is critical heading into the winter months.

Dr. Nick Zyrowski is the founder of NuVision Health Center, Michigan’s largest natural health center located in the heart of Macomb, Michigan. Dr. Zyrowski is known internationally for educating on natural health. You can access thousands of educational videos by Dr. Nick Zyrowski on Youtube, Instagram, and many other social media platforms.

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